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副教授

張禹

基本情況

姓名: 張禹
職稱: 副教授
最高學曆: 研究生
最高學位: 博士
主頁: zy26.github.io
Email: zy26@jlu.edu.cn

詳細情況

講授課程: C#、.NET、Python、數學建模、計算方法、機器學習、生物信息學、計算生物學等。
教育經曆: (1) 2003-09 至 2006-06, 伟德国际BETVlCTOR, 計算數學, 博士
(2) 2001-09 至 2003-07, 伟德国际BETVlCTOR, 計算數學, 碩士
(3) 1997-09 至 2001-07, 伟德国际BETVlCTOR, 計算數學及其應用軟件, 學士
工作經曆: (1) 2017-09 至 今, 伟德国际BETVlCTOR, 伟德国际BETVlCTOR, 副教授
(2) 2018-07 至 2019-07, 美國印第安納大學醫學院, 醫學和分子遺傳學系, 訪問學者
(3) 2007-12 至 2013-09, 伟德国际BETVlCTOR, 計算機科學與技術博士後流動站, 博士後
(4) 2006-07 至 2017-09, 伟德国际BETVlCTOR, 伟德国际BETVlCTOR, 講師
(5) 2011-07 至 2012-07, 美國佐治亞大學, 生物化學與分子生物學系, 訪問學者
科研項目: 近五年主持或參加的國家自然科學基金項目/課題:
(1) 國家自然科學基金委員會, 面上項目, 61972175, 基于雙聚類算法在癌症藥物篩選及臨床轉錄組數據上的代償性耐藥機制研究, 2020-01-01 至 2023-12-31, 59萬元, 在研, 主持
(2) 國家自然科學基金委員會, 面上項目, 61872418, 基于多維度組學數據的腫瘤标志物識别與挖掘方法研究, 2019-01-01 至 2022-12-31, 63萬元, 在研, 參與
(3) 國家自然科學基金委員會, 面上項目, 61772227, 蛋白質結合位點多結構比對與結構⚜⭐〰✝方法研究, 2018-01-01 至 2021-12-31, 62萬元, 在研, 參與
獲獎情況: 獲全國商業科技進步一等獎1項、三等獎1項

Recent Publications

M3S: A comprehensive model selection for multi-modal single-cell RNA sequencing data Y Zhang, C Wan, P Wang, W Chang, Y Huo, J Chen, Q Ma, S Cao, … BMC Bioinformatics 20 (Suppl 24), 672 1 2019

QUBIC2: a novel and robust biclustering algorithm for analyses and interpretation of large-scale RNA-Seq data J Xie, A Ma, Y Zhang, B Liu, S Cao, C Wang, J Xu, C Zhang, Q Ma Bioinformatics 36 (4), 1143–1149 5* 2019

LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data C Wan, W Chang, Y Zhang, F Shah, X Lu, Y Zang, A Zhang, S Cao, … Nucleic acids research 47 (18), e111-e111 3 2019

A new deconvolution algorithm for accurate assessing immune and stromal cell populations in mouse transcriptomic data X Lu, S Tu, W Chang, Y Huo, P Wang, Y Zhang, C Zhang, S Cao Cancer Research 79 (13 Supplement), 2453-2453 2019

A semi-supervised approach for cell phenotypic and functional estimation in tissue microenvironment W Chang, C Wan, Y Zhang, K So, B Richardson, Y Sun, X Zhang, … bioRxiv, 426593 1 2019

Multi-label deep learning for gene function annotation in cancer pathways R Guan, X Wang, MQ Yang, Y Zhang, F Zhou, C Yang, Y Liang Scientific reports 8 (1), 267 10 2018

ICTD: Inference of cell types and deconvolution–a next-generation deconvolution method for accurate assess cell population and activities in tumor microenvironment. W Chang, C Wan, Y Zhang, K So, B Richardson, Y Sun, X Zhang, … bioRxiv, 426593 1 2018

MRHCA: a nonparametric statistics based method for hub and co-expression module identification in large gene co-expression network Y Zhang, S Cao, J Zhao, B Alsaihati, Q Ma, C Zhang Quantitative Biology 6 (1), 40-55 2 2018

QUBIC: a bioconductor package for qualitative biclustering analysis of gene co-expression data Y Zhang, J Xie, J Yang, A Fennell, C Zhang, Q Ma Bioinformatics 33 (3), 450-452 42 2017

RNA-TVcurve: a Web server for RNA secondary structure comparison based on a multi-scale similarity of its triple vector curve representation Y Li, X Shi, Y Liang, J Xie, Y Zhang, Q Ma BMC bioinformatics 18 (1), 51 6 2017

Analyzing gene expression time-courses based on multi-resolution shape mixture model Y Li, Y He, Y Zhang Mathematical Biosciences 281, 74-81 2016

Comprehensive characterization of the genomic alterations in human gastric cancer J Cui, Y Yin, Q Ma, G Wang, V Olman, Y Zhang, WC Chou, CS Hong, … International Journal of Cancer 137 (1), 86-95 47 2015

Bridger: a new framework for de novo transcriptome assembly using RNA-seq data Z Chang, G Li, J Liu, Y Zhang, C Ashby, D Liu, CL Cramer, X Huang Genome biology 16 (1), 30 172 2015

CINPER: An Interactive Web System for Pathway Prediction for Prokaryotes X Mao, X Chen, Y Zhang, S Pangle, Y Xu PloS one 7 (12), e51252 6 2012

SEAS: A system for SEED-based pathway enrichment analysis X Mao, Y Zhang, Y Xu PloS one 6 (7), e22556 5 2011

Analysis of gene expression data based on density and biological knowledge X Zhou, H Sun, DP Wang, Y Zhang, Y Zhou Frontier of Computer Science and Technology (FCST), 2010 Fifth International … 1 2010

Gender Classification with Support Vector Machines Based on Non-tensor Pre-wavelets L Ying, Z Yu, Z Shishun Computer Research and Development, 2010 Second International Conference on … 3 2010

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